Contrast protocols & bolus timing

Why you inject fast, where you put the IV, and the two methods used to time the scan to peak coronary opacification.

Contrast differentiates blood from soft tissue. The goal is to preferentially opacify the left heart and coronary arteries while avoiding streak from a too-bright right heart. High injection rates of 5–7 cc/sec through at least an 18 G IV in the right arm are required for maximum attenuation.

1 Scan timing techniques

  • Test bolus. A small initial injection (≈ 20 cc) paired with a single-slice fluoroscopy scan explicitly measures the patient’s circulation time before the primary scan.
  • Bolus tracking. A region-of-interest tracker monitors a target (usually the ascending aorta); once contrast brightness crosses a threshold (typically 100–175 HU), the actual scan triggers automatically.
  • Saline chaser. Following the contrast bolus with a saline chaser (biphasic or triphasic protocol) improves arterial enhancement, maintains contrast density, and limits streak artifact in the right heart.
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Scan acquisition & gating
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Image reconstruction & artifacts