For a successful cardiac CT, the patient must be able to:
- Hold still
- Lift both arms above the shoulders
- Follow breathing instructions — moderate inspiration without bearing down
- Receive iodinated contrast and rate-controlling medications
1 Pharmacology
- Beta-blockers (e.g. metoprolol) or calcium-channel blockers (e.g. diltiazem) to lower the heart rate below 70 bpm, prolonging the diastolic rest period needed for a motion-free image.
- Nitroglycerin concurrently for coronary vasodilation.
2 Appropriate use
CCTA is most appropriate for:
- Excluding CAD in symptomatic patients with low-to-intermediate pre-test probability
- Evaluating structural morphology — TAVR planning, bypass graft patency
- Cases where prior stress testing is equivocal
3 Inappropriate use
Generally contraindicated for:
- Asymptomatic low-risk patients (for full contrast angiograms)
- Severe renal failure (Cr > 1.8)
- Severe contrast anaphylaxis
- Uninterpretable high heart rates
- Morbid obesity (BMI > 40)
- High pre-test probability cases where invasive catheterization would be definitively preferred